Hesperetin (Hesperetol)

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Hesperetin is a bioflavonoid and, to be more specific, a flavanone. Hesperidin (a flavonone glycoside) is water-soluble due to the presence of the sugar part in its structure, so on ingestion it releases its aglycone. Although not as juicy or delicious as the inside of an orange, the peel is edible, and has been consumed particularly in environments where there is scarcity of resources and where maximum nutritional value must be derived and minimal waste generated (for example, on a submarine). The peel of an orange has increased vitamin C and fiber. Most of the vitamin C is located in the zest rather than the pith. However, high concentrations of pesticides have been found in orange peels. Some organizations recommend that one should only consume the peels of organically grown and processed oranges, where chemical pesticides or herbicides would not have been used on the peel. Orange peel contains citral, an aldehyde that antagonizes the action of vitamin A. Therefore, anyone eating orange peels should make certain that their dietary intake of Vitamin A is sufficient.


1. Hesperetin is a potent antioxidant against peroxynitrite.
2. Hesperetin have the effect of anti-inflammatory. Hesperetin can indirect inhibit the inflammatory reaction by inhibiting the release of a rachidonic acid metabolite and histamine.
3. Hesperetin can prevent blood platelet agglutination, prophylaxis the formation of thrombus and protect Cardiovascular system. Hesperidin can also act as a vasodilator, which may be useful in Hypertension.
4. Hesperetin and naringenin have Lipid-lowering efficacy.


1. Applied in cosmetics field;
2. Applied in pharmaceutical field;
3. Applied in health care products field;
4. Applied in food field;

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Xi'an Nature Herb Bio-Tech Co.,Ltd

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